Perovskite-gold Shell Composite Nanoprobe for Trimodal Lateral Flow Immunoassay Detection of SARS-CoV-2 Antibodies

Key Points

• The aim is to develop a nanoprobe that enables effective detection of SARS-CoV-2 antibodies using multiple signaling modes.
• Developed a CsPbBr3@SiO2-Aushell nanoprobe.
• Conducted a trimodal immunochromatographic assay.
• Utilized colorimetric, fluorescent, and photothermal signals for detection.
• Achieved detection of SARS-CoV-2 IgG antibodies.
• Photothermal mode provided the highest sensitivity.
• Demonstrated environmental adaptability and internal verification.