Perovskite-gold Shell Composite Nanoprobe for Trimodal Lateral Flow Immunoassay Detection of SARS-CoV-2 Antibodies

Xin Wang; Zhi Tong; Hongyu Liu; Hongwei Zhang; Xin Luo; Jingbin Zeng

doi:10.1039/d5cc07358h

January 1, 2026Chemical Communications

Perovskite-gold Shell Composite Nanoprobe for Trimodal Lateral Flow Immunoassay Detection of SARS-CoV-2 Antibodies

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Key Points

The aim is to develop a nanoprobe that enables effective detection of SARS-CoV-2 antibodies using multiple signaling modes.
Developed a CsPbBr3@SiO2-Aushell nanoprobe.
Conducted a trimodal immunochromatographic assay.
Utilized colorimetric, fluorescent, and photothermal signals for detection.
Achieved detection of SARS-CoV-2 IgG antibodies.
Photothermal mode provided the highest sensitivity.
Demonstrated environmental adaptability and internal verification.

Implication

Demonstrates a trimodal assay for SARS-CoV-2 IgG detection, indicating enhanced signal verification and adaptability.

Abstract

A CsPbBr3@SiO2-Aushell nanoprobe enables trimodal (colorimetric/fluorescent/photothermal) lateral flow immunochromatographic assay for SARS-CoV-2 IgG detection. This multi-signal approach offers environmental adaptability and internal cross-verification, with the photothermal mode achieving the highest...

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/698d6e055be6419ac0d5374e https://doi.org/10.1039/d5cc07358h

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Perovskite-gold Shell Composite Nanoprobe for Trimodal Lateral Flow Immunoassay Detection of SARS-CoV-2 Antibodies

Key Points

Implication

Abstract

Discussion

Cite This Study

Perovskite-gold Shell Composite Nanoprobe for Trimodal Lateral Flow Immunoassay Detection of SARS-CoV-2 Antibodies

Key Points

Implication

Abstract

Discussion

Cite This Study

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