Quasi-isostructural Order-disorder Phase Transitions and Anisotropic Thermal Expansions in Polymorphic Crystals of a Biologically Active Molecule with Distinct Solubility and Dissolution Rate

Key Points

• The research investigates phase transitions and thermal expansions in polymorphic crystals of a biologically active molecule.
• Analyzed order-disorder phase transitions in single-component organic crystals.
• Observed thermal expansions and solubility characteristics.
• Compared dissolution rates across different crystalline forms.
• Identified unique order-disorder transitions in the studied polymorphic crystals.
• Demonstrated notable anisotropic thermal expansions.
• Showed variations in solubility and dissolution rates depending on crystal form.