What question did this study set out to answer?

The research investigates phase transitions and thermal expansions in polymorphic crystals of a biologically active molecule.

February 14, 2026Materials Advances0 citationsOpen Access

Quasi-isostructural Order-disorder Phase Transitions and Anisotropic Thermal Expansions in Polymorphic Crystals of a Biologically Active Molecule with Distinct Solubility and Dissolution Rate

AVAditya VermaShiv Nadar University S.Sourabh .Shiv Nadar University AKAnil KumarShiv Nadar University

Key Points

The research investigates phase transitions and thermal expansions in polymorphic crystals of a biologically active molecule.
Analyzed order-disorder phase transitions in single-component organic crystals.
Observed thermal expansions and solubility characteristics.
Compared dissolution rates across different crystalline forms.
Identified unique order-disorder transitions in the studied polymorphic crystals.
Demonstrated notable anisotropic thermal expansions.
Showed variations in solubility and dissolution rates depending on crystal form.

Abstract

Order-disorder phase transitions are common in inorganic and hybrid materials, but rarely occur in single-component purely organic molecular crystals and are scarce in polymorphic crystals of biologically active molecules. Herein,...

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