What question did this study set out to answer?

February 17, 2026

Markovnikov-Selective Hydroboration of Unactivated Alkenes via MHAT under Cobalt/Photoredox Dual Catalysis

Key Points

To develop a method for Markovnikov-selective hydroboration of unactivated alkenes using dual catalysis.
Employ Markovnikov-selective hydroboration using MHAT
Utilize cobalt and photoredox dual catalysis
Investigate the reaction across mono-, di-, and trisubstituted alkenes
Achieve high regioselectivity in hydroboration
Generate alkyl boronic esters from unactivated alkenes
Utilize radical intermediates to facilitate the reaction

Abstract

Catalytic Markovnikov-selective hydroboration of unactivated alkenes is a powerful tool for accessing alkyl boronic esters. Here, we report Markovnikov-selective MHAT hydroboration of unactivated alkenes enabled by cobalt/photoredox dual catalysis. The reaction proceeded via radical intermediates, providing high regioselectivity with mono-, di-, and trisubstituted alkenes.

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

Yusuke Seino

Shintaro Dozen

Tatsuhiko Yoshino

Journals

Organic Letters

Actions

Institutions

Kyoto University

Hokkaido University

Graduate School USA

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Markovnikov-Selective Hydroboration of Unactivated Alkenes via MHAT under Cobalt/Photoredox Dual Catalysis

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study