Prophylactic carbetocin versus oxytocin following vaginal delivery among women with high risk for postpartum hemorrhage: A before-and-after study.

Key Points

• The study aims to compare the effectiveness of carbetocin versus oxytocin in preventing postpartum hemorrhage (PPH) after vaginal delivery in high-risk women.
• Before-and-after study design
• Comparison of carbetocin and oxytocin as prophylactic agents
• Population consists of high-risk women delivering vaginally
• Assessment of PPH rates and use of additional interventions
• Carbetocin showed a similar rate of postpartum hemorrhage compared to oxytocin
• Significantly reduced the need for oxytocin when used as the first-line agent
• No difference in the use of prostaglandins or invasive procedures for managing persistent PPH