Integrative Analysis of Bacterial Diversity in Patients with Type 2 Diabetes Mellitus and Periodontitis Using a Case-Control Microbiome Approach | Synapse
February 28, 2026Open Access
Integrative Analysis of Bacterial Diversity in Patients with Type 2 Diabetes Mellitus and Periodontitis Using a Case-Control Microbiome Approach
Key Points
The research aims to investigate the relationship between bacterial diversity and type 2 diabetes mellitus (T2DM) in the context of periodontitis.
Conducted a case-control microbiome analysis.
Analyzed salivary samples from patients with T2DM and periodontitis.
Identified bacterial taxa and functional pathways.
Detected significant shifts in salivary microbial composition in T2DM patients.
Linked specific taxa to the presence of periodontitis.
Predicted functional pathways associated with altered microbial diversity.
Abstract
T2DM is associated with distinct shifts in salivary microbial composition and predicted function, revealing taxa and pathways linked to periodontitis.