What question did this study set out to answer?

This study examines the relationship between delayed Sylvian fissure maturation and expected brain oxygen saturation in fetuses with congenital heart disease.

March 1, 2026

Fetal Sylvian Fissure Maturation in Congenital Heart Disease and Its Relation to Expected Brain Arterial Oxygen Saturation: A Longitudinal Study.

Key Points

This study examines the relationship between delayed Sylvian fissure maturation and expected brain oxygen saturation in fetuses with congenital heart disease.
Longitudinal assessment of fetal development
Measurement of Sylvian fissure depth
Calculation of SF depth/insula depth ratio and SF depth/HC ratio
Monitoring cerebral arterial oxygen saturation (SaO<sub>2</sub>)
Fetuses with congenital heart disease exhibit delayed development of the Sylvian fissure
Reduced expected arterial oxygen saturation correlates with delayed fissure maturation
Assessment methods for cortical folding show reliable results.

Abstract

Delayed SF development in fetuses with CHD may be associated with the expected cerebral arterial SaO2 reduction. Prenatal cortical folding can be reliably assessed by the SF depth/insula depth ratio or the SF depth/HC ratio.

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Cite This Study

Xiong et al. (Wed,) studied this question.

synapsesocial.com/papers/69a3d8b8ec16d51705d2fe0b https://doi.org/https://doi.org/10.1002/pd.70100

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