METTL16 antagonizes astaxanthin-induced ferroptosis in colorectal cancer cells | Synapse
March 3, 2026Open Access
METTL16 antagonizes astaxanthin-induced ferroptosis in colorectal cancer cells
Key Points
Astaxanthin significantly inhibits colorectal cancer cell growth, impacting treatment potential.
Key evidence demonstrated a relationship between METTL16 and ferroptosis in astaxanthin-treated cells.
Assessment reveals astaxanthin's effects on CRC and its mechanism via METTL16 modulation.
Highlights the importance of understanding ferroptosis in the context of colorectal cancer therapies.
Abstract
This study demonstrates that astaxanthin inhibits CRC cell growth and delineates its relationship and mechanisms with METTL16 and ferroptosis, providing a new direction for CRC treatment.