Maternal pregnancy complications and offspring autism spectrum disorder risk: an umbrella review

Key Points

• Offspring autism spectrum disorder risk correlates significantly with maternal pregnancy complications such as gestational diabetes and hypertension.
• Maternal complications revealed increased odds ratios, with some complications showing a 1.5 to 3 times higher risk in offspring.
• Umbrella review of existing literature provides comprehensive insights into the connection between maternal conditions and autism risk in children.
• Findings emphasize the need for healthcare focus on maternal health to potentially lower autism spectrum disorder prevalence.