Maternal pregnancy complications and offspring autism spectrum disorder risk: an umbrella review

Manman Zhu; Hao Yang; Bo Feng; Yi Jiang; Yaoyao Zhang

doi:10.1016/j.psychres.2026.116987

January 30, 2026Psychiatry Research

Maternal pregnancy complications and offspring autism spectrum disorder risk: an umbrella review

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Key Points

Offspring autism spectrum disorder risk correlates significantly with maternal pregnancy complications such as gestational diabetes and hypertension.
Maternal complications revealed increased odds ratios, with some complications showing a 1.5 to 3 times higher risk in offspring.
Umbrella review of existing literature provides comprehensive insights into the connection between maternal conditions and autism risk in children.
Findings emphasize the need for healthcare focus on maternal health to potentially lower autism spectrum disorder prevalence.

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Implication

Umbrella review highlights increased autism spectrum disorder risk due to maternal pregnancy complications, suggesting a critical area for prevention.

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Cite This Study

Zhu et al. (2026) studied this question.

synapsesocial.com/papers/69a75f05c6e9836116a2a1a7 https://doi.org/10.1016/j.psychres.2026.116987

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Maternal pregnancy complications and offspring autism spectrum disorder risk: an umbrella review

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Maternal pregnancy complications and offspring autism spectrum disorder risk: an umbrella review

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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