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This research examines the effects of regional nodal irradiation on lymphedema and surgical outcomes in patients undergoing lymphatic reconstruction following mastectomy.

March 6, 2026Journal of Reconstructive Microsurgery0 citations

Regional Nodal Irradiation Impact on Lymphedema, Surgical Outcomes and Quality-of-Life Following Mastectomy, Axillary Dissection and Immediate Lymphatic Reconstruction

AHAbbas M. HassanDhofar University JHJohn P Hajj JLJohn P. LewisUniversity of Arkansas at Little Rock

Key Points

This research examines the effects of regional nodal irradiation on lymphedema and surgical outcomes in patients undergoing lymphatic reconstruction following mastectomy.
Retrospective analysis of patient outcomes
Comparison of lymphedema rates and surgical morbidity
Assessment of patient-reported quality-of-life outcomes
No increase in lymphedema rates among patients receiving regional nodal irradiation
Surgical morbidity remained stable irrespective of the intervention
Patient-reported outcomes were not adversely affected by regional nodal irradiation

Abstract

RNI in the setting of ILR was not associated with increased surgical morbidity, lymphedema rates, or adverse patient-reported outcomes. While ILR may mitigate the expected morbidity of RNI, prospective studies are needed to establish its definitive value in this high-risk population.

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Hassan et al. (Tue,) studied this question.

synapsesocial.com/papers/69aa70c8531e4c4a9ff5ae84 https://doi.org/https://doi.org/10.1055/a-2824-6558

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