Congenital Central Hypoventilation Syndrome with Recurrent Syncope Requiring Pacemaker Implantation: A Case Report

Key Points

• To report a case of a child with congenital central hypoventilation syndrome (CCHS) who experienced recurrent syncope necessitating pacemaker implantation.
• Case report of a 5-year-old girl diagnosed with CCHS via genetic testing identifying a PHOX2B mutation.
• Implementation of home ventilatory support before developing syncope episodes.
• Pacemaker implantation (VVI mode) performed at age 5 due to recurrent syncope episodes related to bradyarrhythmia.
• The child experienced multiple episodes of syncope prior to pacemaker implantation.
• Post-implantation, the child had no further episodes of syncope.
• The case suggests a correlation between bradyarrhythmia and symptoms in children with CCHS.