In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

Key Points

• The aim is to investigate the activity of innate immune cells in the pancreas using PET imaging in type 1 diabetes.
• Utilized PET imaging to assess innate immune cell activity in pancreatic tissue.
• Compared immune activity in new-onset and long-standing type 1 diabetes.
• Analyzed tracer uptake as a marker for immune cell activity.
• No increased macrophage or neutrophil activity was found in new-onset type 1 diabetes.
• Long-standing type 1 diabetes showed increased tracer uptake, indicating higher immune activity and potential fibrosis.