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PET imaging reveals pancreatic immune activity differences in new-onset and long-standing type 1 diabetes, suggesting distinct disease stages.
PET imaging of innate immune cells in the pancreas is feasible. While no increased macrophage or neutrophil activity was observed in new-onset T1D, increased tracer uptake in long-standing T1D may reflect late-stage inflammatory processes and fibrosis.
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Anvari et al. (2026) studied this question.
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