Browser extension
Synapse, beside the paper you’re reading
Open a paper on a supported journal or preprint site and Synapse opens a panel next to it. Ask questions answered from the article, and see its key findings and PICO when Synapse has them, without leaving the publisher’s page.
Chrome, Edge, Brave and Arc install from the Chrome Web Store; Safari from the App Store.
Free for clinicians, fellows and researchers. Sign in with your Synapse account to save papers to your library.

What it does on the page

Ask about the paper you have open
Answers come from the article itself, with inline citations to the sources. Tap a suggested question or type your own.

See where it sits in the literature
A graph and a ranked list of similar studies, with similarity scores, so you can see what else to read.
From the same panel you can save the paper to your Synapse library, copy a citation in the style your field uses, share it, or open the full analysis on Synapse.
How to start
- 1
Add the extension
From the Chrome Web Store or the App Store. It takes a few seconds.
- 2
Pin it to your toolbar
In Chrome, open the puzzle-piece menu and pin Synapse. In Safari, allow it on the sites you read.
- 3
Open a paper
On a supported journal or preprint site, click the Synapse icon and the panel opens beside the article.
Chrome, Edge, Brave and Arc install from the Chrome Web Store; Safari from the App Store.
Synapse