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The production of systematic reviews and meta-analyses has reached epidemic proportions. Possibly, the large majority of produced systematic reviews and meta-analyses are unnecessary, misleading, and/or conflicted.
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John P. A. Ioannidis
Stanford University
Milbank Quarterly
Stanford University
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John P. A. Ioannidis (Thu,) studied this question.
synapsesocial.com/papers/69d91f288988aeabbe6842e2 — DOI: https://doi.org/10.1111/1468-0009.12210
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: