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April 12, 2026Open Access

Structure–Activity Relationships of Morpholine-Modified Silicon(IV) Phthalocyanines as Potential Antidiabetic Agents

Key Points

The aim is to explore the effectiveness of morpholine-modified silicon(IV) phthalocyanines as potential agents for treating type 2 diabetes.
Synthesis of morpholine-modified silicon(IV) phthalocyanines.
Evaluation of their biological activity related to diabetes.
Comparison of effectiveness against existing antidiabetic drugs.
Certain compounds demonstrated significant antidiabetic activity.
Morpholine modifications enhanced biological effectiveness.
The findings suggest a novel approach for diabetes management.

Abstract

Type 2 diabetes mellitus (DM) is a chronic metabolic disorder with a rapidly increasing global prevalence, highlighting the need for safer and more effective therapeutic strategies. In this study, a...

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Keleş et al. (Thu,) studied this question.

synapsesocial.com/papers/69db37b04fe01fead37c5bc4 https://doi.org/https://doi.org/10.1039/d6dt00405a

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