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April 12, 2026Dalton Transactions0 citationsOpen Access

Structure–Activity Relationships of Morpholine-Modified Silicon(IV) Phthalocyanines as Potential Antidiabetic Agents

TKTurgut KeleşZBZekeriya BıyıklıoğluGSGökçe Seyhan

Key Points

  • The aim is to explore the effectiveness of morpholine-modified silicon(IV) phthalocyanines as potential agents for treating type 2 diabetes.
  • Synthesis of morpholine-modified silicon(IV) phthalocyanines.
  • Evaluation of their biological activity related to diabetes.
  • Comparison of effectiveness against existing antidiabetic drugs.
  • Certain compounds demonstrated significant antidiabetic activity.
  • Morpholine modifications enhanced biological effectiveness.
  • The findings suggest a novel approach for diabetes management.

Abstract

Type 2 diabetes mellitus (DM) is a chronic metabolic disorder with a rapidly increasing global prevalence, highlighting the need for safer and more effective therapeutic strategies. In this study, a...

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Cite This Study

Keleş et al. (2026) studied this question.

synapsesocial.com/papers/69db37b04fe01fead37c5bc4https://doi.org/10.1039/d6dt00405a
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