What question did this study set out to answer?

This analysis compares the safety and outcomes of partial nephrectomy versus radical nephrectomy in patients with cT2 renal cell carcinoma.

April 13, 2026

sPaRT2 – Minimally Invasive Partial versus Radical Nephrectomy for cT2 Renal Cell Carcinoma: A National Matched-Pair Analysis (UroCCR 235)

Key Points

This analysis compares the safety and outcomes of partial nephrectomy versus radical nephrectomy in patients with cT2 renal cell carcinoma.
Conducted a national matched-pair analysis.
Compared outcomes of patients undergoing minimally invasive partial nephrectomy (RAPN) and radical nephrectomy (RN).
Evaluated perioperative morbidity and long-term nephron-sparing benefits.
RAPN shown to be safe and functionally superior to RN for selected patients.
Higher perioperative morbidity associated with RAPN, yet considered acceptable in expert centers.
Long-term benefits from nephron-sparing procedures outweigh perioperative risks.

Abstract

RAPN is a safe and functionally superior alternative to RN for selected patients with cT2 RCC. While associated with higher perioperative morbidity, these risks are acceptable in expert centers and offset by long-term nephron-sparing benefits.

sPaRT2 – Minimally Invasive Partial versus Radical Nephrectomy for cT2 Renal Cell Carcinoma: A National Matched-Pair Analysis (UroCCR 235)

Key Points

Abstract

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