Comparison of the Results of the Treatment of Adolescents and Young Adults With Standard-Risk Acute Lymphoblastic Leukemia With the Programa Español de Tratamiento en Hematología Pediatric-Based Protocol ALL-96

Key Points

• To compare treatment outcomes of adolescents and young adults with standard-risk acute lymphoblastic leukemia using the pediatric ALL-96 protocol.
• Comparison of treatment responses in adolescents and young adults with SR ALL using the ALL-96 protocol.
• Assessment of hematologic toxicity levels between both age groups.
• Analysis of age-unrestricted use of pediatric treatment regimens.
• Response to the ALL-96 protocol was identical for both age groups.
• Increased hematologic toxicity was noted in young adults compared to adolescents.
• Findings support the use of pediatric regimens in treating older patients with SR ALL.