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Comparison of the Results of the Treatment of Adolescents and Young Adults With Standard-Risk Acute Lymphoblastic Leukemia With the Programa Español de Tratamiento en Hematología Pediatric-Based Protocol ALL-96

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To compare treatment outcomes of adolescents and young adults with standard-risk acute lymphoblastic leukemia using the pediatric ALL-96 protocol.
Comparison of treatment responses in adolescents and young adults with SR ALL using the ALL-96 protocol.
Assessment of hematologic toxicity levels between both age groups.
Analysis of age-unrestricted use of pediatric treatment regimens.
Response to the ALL-96 protocol was identical for both age groups.
Increased hematologic toxicity was noted in young adults compared to adolescents.
Findings support the use of pediatric regimens in treating older patients with SR ALL.

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Randomized trial compares treatment response in adolescents and young adults with ALL, suggesting pediatric protocols can be widely used.

Ribera et al. (2008) studied this question.

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