What question did this study set out to answer?

The research aims to explore the relationship between metal elements and cardiometabolic diseases via free fatty acids.

April 18, 2026Open Access

Serum free fatty acids mediate the association between metal elements and cardiometabolic diseases

YMYayuan Mei ZLZheyuan LiuHebei Medical University XCXiaobao ChenHubei University of Science and Technology

Key Points

The research aims to explore the relationship between metal elements and cardiometabolic diseases via free fatty acids.
Examined the connection between metallomics and free fatty acids (FFAs)
Analyzed associations between metal elements and cardiometabolic disease markers
Identified free fatty acids as potential biomarkers for metal exposure
Demonstrated a mediating role of FFAs in the association with cardiometabolic diseases

Abstract

Our findings provide exploratory evidence connecting metallomics with FFAs and cardiometabolic diseases, suggesting FFAs as potential biomarkers for metal exposure and cardiometabolic diseases prevention.

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