2-Pyridyl Sulfoxide Directed Pd(II)-Catalyzed Regioselective C2- Arylation/Alkenylation of Indoles

Key Points

• The aim is to explore a new Pd(II)-catalyzed method for regioselective modifications of indoles.
• Utilized Pd(II) as a catalyst for reactions.
• Employed 2-pyridyl sulfoxide as a directing group.
• Conducted reactions with iodoarenes and both activated and unactivated alkenes.
• Achieved regioselective C2-arylation and alkenylation of indoles.
• Demonstrated effectiveness with various iodoarenes and alkenes.