Does global left ventricular afterload impact left ventricular function in asymptomatic severe aortic stenosis?
Asymptomatic patients with severe aortic stenosis (AS)
Assessment of global left ventricular afterload using two-dimensional speckle-tracking echocardiography
Myocardial systolic impairment / intrinsic myocardial dysfunctionsurrogate
In asymptomatic severe aortic stenosis, LV ejection fraction underestimates myocardial systolic impairment, highlighting the value of speckle-tracking echocardiography to detect intrinsic dysfunction related to increased global LV afterload.
In asymptomatic patients with severe AS, LV ejection fraction markedly underestimates the extent of myocardial systolic impairment. Intrinsic myocardial dysfunction is particularly common in patients with increased global LV afterload, and especially in the subset of patients with low-flow AS.
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P. Lancellotti
Centre Hospitalier Universitaire de Liège
Erwan Donal
Cardiac Imaging
J. Magné
Inserm
European Journal of Echocardiography
Centre Hospitalier Universitaire de Liège
Hôpital Pontchaillou
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Lancellotti et al. (Thu,) studied this question.
synapsesocial.com/papers/69effb60afa91c76b5d0a860 — DOI: https://doi.org/10.1093/ejechocard/jeq014