Correction for Delay and Dispersion Results in More Accurate Cerebral Blood Flow Ischemic Core Measurement in Acute Stroke

BACKGROUND AND PURPOSE: This study aimed to assess how the ischemic core measured by perfusion computed tomography (CTP) was affected by the delay and dispersion effect. METHODS: test; their respective ability to predict good clinical outcome (3-month modified Rankin Scale score) was tested in logistic regression. RESULTS: <0.001), with 12 patients classified as favorable imaging patterns by ddCBF but as unfavorable by sCBF. The favorable imaging pattern classified by ddCBF, compared with sCBF classification, had higher predictive power for good clinical outcome (odds ratio, 7.8 2-30.5 and 3.1 0.9-11, respectively). CONCLUSIONS: Delay and dispersion correction increases the accuracy of ischemic core measurement on CTP.