Does the Total Thrombus-formation Analysis System predict periprocedural bleeding events in patients with coronary artery disease undergoing percutaneous coronary intervention?
The Total Thrombus-formation Analysis System is suggested as a potentially useful predictor of periprocedural bleeding events in CAD patients undergoing elective PCI.
BACKGROUND: Periprocedural bleeding events are common after percutaneous coronary intervention. We evaluated the association of periprocedural bleeding events with thrombogenicity, which was measured quantitatively by the Total Thrombus-formation Analysis System equipped with microchips and thrombogenic surfaces (collagen, platelet chip PL; collagen plus tissue factor, atheroma chip AR). METHODS AND RESULTS: levels in 127 patients of the radial approach group were not significantly different in patients with or without periprocedural bleeding events. CONCLUSIONS: measured by the Total Thrombus-formation Analysis System is a potentially useful predictor of periprocedural bleeding events in coronary artery disease patients undergoing elective percutaneous coronary intervention.
Oimatsu et al. (Wed,) studied this question.
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