Application of various ylides in the 4+1 cycloaddition of enaminothiones and N-thioacylformamidines for constructing substituted thiophenes and thiazoles

Key Points

• This research aims to develop a cycloaddition method using ylides to synthesize substituted thiophenes and thiazoles.
• Developed cycloaddition of enaminothiones and N-thioacylformamidines with various ylides.
• Synthesized products achieved yields between 61% and 84%.
• Successfully constructed various thiophenes and thiazoles with multiple derivatives.
• Yield achieved ranged from 61% to 84% for different product variations.