Compliance with anti-hypertensive therapy was associated with significantly better blood pressure control compared to non-compliance (45.9% vs 27.3%, p=0.007).
Cross-Sectional (n=225)
No
What is the compliance rate and what factors affect non-compliance with anti-hypertensive therapy in Nigerian patients?
Non-compliance with anti-hypertensive therapy is common (34.2%) among Nigerian patients, largely driven by patient attitudes, beliefs, and lack of finances, and is associated with poorer blood pressure control.
Absolute Event Rate: 45.9% vs 27.3%
p-value: p=0.007
BACKGROUND: Non-compliance with antihypertensive drug therapy can have a negative impact on cardiovascular outcome. The objective of this study was to determine compliance rate with anti-hypertensive therapy and factors affecting compliance among patients attending a Nigerian tertiary hospital. METHODS: A cross sectional study was conducted on 225 black hypertensive patients attending a tertiary clinic in Lagos, Nigeria. Demographic data, current anti-hypertensive therapy, compliance with prescribed therapy, factors affecting compliance and BP were documented via an investigator administered questionnaire and open-ended interviews. RESULTS: In this study, 77(34.2%) of the hypertensive patients were non-compliant. Blood pressure control was significantly better among compliant patients (45.9%) than in non-compliant patients (27.3%) (x(2) = 7.35 p=0.007). Gender, age, number of drugs used, educational level and presence of co-morbidities did not affect compliance. The major reasons for non-compliance were miscellaneous factors (60%) related to both patient's attitudes and beliefs (reflecting ignorance),and consultation failure on the part of clinicians. Lack of finances and side effects of medications accounted for 23.8% and 16.2% of non-compliances respectively. CONCLUSION: Although lack of finances is the single most self reported reason, miscellaneous factors related to patients' attitudes and belief contribute frequently. Incorporating patient education and counselling in routine follow-up may improve compliance, BP control, and ultimately impact positively on cardiovascular outcome.
Amira et al. (Mon,) conducted a cross-sectional in Hypertension (n=225). Anti-hypertensive drug therapy compliance vs. Non-compliance was evaluated on Blood pressure control (p=0.007). Compliance with anti-hypertensive therapy was associated with significantly better blood pressure control compared to non-compliance (45.9% vs 27.3%, p=0.007).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: