Three patients with Duchenne muscular dystrophy developed hypertrophic cardiomyopathy, demonstrating the rare combined pathology of these two disorders in a longitudinal case series.
Case Report (n=3)
This case series expands upon previous reports by describing longitudinal findings in three patients with Duchenne muscular dystrophy who developed hypertrophic cardiomyopathy.
Duchenne muscular dystrophy is characterised by fibrofatty replacement of muscle, resulting in dilated cardiomyopathy. Hypertrophic cardiomyopathy affects 1:200-1:500 people and is characterised by asymmetric ventricular septal hypertrophy. To date, there have been two separately reported cases describing the combined pathology of these disorders. Herein, we expand upon these reports with a case series describing longitudinal findings in three patients with Duchenne muscular dystrophy who developed hypertrophic cardiomyopathy.
Greiner et al. (Tue,) conducted a case report in Duchenne muscular dystrophy and hypertrophic cardiomyopathy (n=3). Three patients with Duchenne muscular dystrophy developed hypertrophic cardiomyopathy, demonstrating the rare combined pathology of these two disorders in a longitudinal case series.
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