Why the study?
Does estimation from casual urine specimens accurately reflect 24-hour urinary sodium excretion in Western populations?
Population
5,693 participants aged 20-59 years from 29 North American and European samples
Comparison
Estimation of 24-hour urinary sodium excretion… vs Observed 24-hour urinary sodium excretion
Design
Cross-sectional, Participants were randomly assigned to test or validation…
Key result
Casual urine specimens estimated 24-hour sodium excretion with population-level correlations of 0.79 (men) and 0.71 (women), and mean biases of -1.8 and 2.2 mmol/24h respectively.
Authors
Loading...
May support casual urine for population sodium estimates; leaves open individual accuracy and prospective validation.
Cross-Sectional (n=5,693)
Randomly assigned to test or validation data sets
Yes
Does estimation from casual urine specimens accurately reflect 24-hour urinary sodium excretion in Western populations?
Casual urine specimens provide a valid, low-burden alternative to 24-hour urine collections for estimating population-level sodium intake, though study-specific calibration is recommended.
Brown et al. (2013) conducted a cross-sectional in General population (n=5,693). Casual (spot) urine specimens vs. 24-hour urine collections was evaluated on Correlation and bias between observed and estimated 24-hour sodium excretion. Casual urine specimens estimated 24-hour sodium excretion with population-level correlations of 0.79 (men) and 0.71 (women), and mean biases of -1.8 and 2.2 mmol/24h respectively.