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April 22, 2022Cureus20 citationsOpen Access

Hyperthyroidism and the Risk of Cardiac Arrhythmias: A Narrative Review

MAMahlika AhmadSRSanjana ReddyZBZineb Barkhane

Key Result

Hyperthyroidism is associated with a significantly increased risk of cardiac arrhythmias, particularly atrial fibrillation which presents in 28% of patients, and sinus tachycardia.

Structured PICO

P
Population
Patients with hyperthyroidism (overt and subclinical)

This narrative review highlights that hyperthyroidism is a significant independent risk factor for cardiac arrhythmias, particularly atrial fibrillation and sinus tachycardia, and outlines current management strategies.

Limitations

  • The review targets only hyperthyroidism as a risk factor with no co-morbidities, not addressing other significant risk factors for cardiac arrhythmias.
  • The study does not address additional hyperthyroidism-related cardiovascular complications.
  • Very few studies have collectively discussed hyperthyroid-induced atrial and ventricular arrhythmias.

Abstract

Hyperthyroidism directly affects the cardiovascular system, altering the heart's normal function and leading to high cardiovascular mortality. Excess thyroid hormones are associated with significantly increased risk and prevalence of cardiac arrhythmias, particularly atrial fibrillation (AF). This article reviewed the hemodynamic changes and the risk of cardiac arrhythmias, including atrial and ventricular arrhythmias associated with hyperthyroidism. It has also discussed the multi-level pathophysiology of thyrotoxic AF, sinus tachycardia, and different treatment modalities such as anti-thyroid drugs, beta-blockers, and the role of cardioversion and catheter ablation. This article has explored different studies that have concluded that AF and sinus tachycardia are the most common arrhythmias associated with thyrotoxicosis.

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Cite This Study

Ahmad et al. (2022) conducted a review in Hyperthyroidism and Cardiac Arrhythmias. Hyperthyroidism vs. Euthyroid state was evaluated. Hyperthyroidism is associated with a significantly increased risk of cardiac arrhythmias, particularly atrial fibrillation which presents in 28% of patients, and sinus tachycardia.

synapsesocial.com/papers/6a156d3a15658026c082584chttps://doi.org/10.7759/cureus.24378
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