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February 5, 1955Journal of the American Medical Association37 citations

Myocardial Infarction: Its Clinical Manifestations and Treatment with Anticoagulants. A Study of 1031 Cases

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Key Points

  • The study aims to investigate the clinical manifestations of myocardial infarction and evaluate the role of anticoagulants in treatment.
  • Analysis of 1031 cases of myocardial infarction with a focus on anticoagulant treatment.

Structured PICO

Do anticoagulants prevent the sequelae of myocardial infarction in patients with myocardial infarction?

P
Population
1031 cases of myocardial infarction
I
Intervention
Anticoagulants
O
Outcome
Prevention of the sequelae of myocardial infarction

This monograph presents a detailed statistical analysis of 1031 cases evaluating the controversial role of anticoagulants in preventing sequelae of myocardial infarction.

Abstract

In this elaborately documented monograph the reader can examine for himself the data and statistical analyses on which the conclusions presented are based. This book represents an important contribution in reporting on a clinical problem and in designing an experiment dealing with such a question—in this case the value of anticoagulants. Although it serves as a milestone in good clinical investigation, this does not imply that the conclusions of the authors will be accepted without controversy. Anyone familiar with the recent literature will recognize that the role of anticoagulants in the prevention of the sequelae of myocardial infarction has generated almost as much heat as light. The protagonists of the two opposite viewpoints, having presented their lines of thought, are now trying to maintain the supremacy of their own positions. It is therefore a pleasure to have documents presented that are critically analyzed and cautiously interpreted. The evidence presented in

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Cite This Study

A 1955 study studied this question.

synapsesocial.com/papers/6a157460b2e0231f1582834ehttps://doi.org/10.1001/jama.1955.02950230067033
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Clinicopathological Study of Acute Myocardial Infarction and the Role of Anticoagulation Therapy1959 · 11 citations
  2. 2The Case for Anticoagulants in Acute Myocardial Infarction1976 · 1 citations
  3. 3Anticoagulants in acute myocardial infarction. Results of a cooperative clinical trial1973 · 49 citations
  4. 4Anticoagulant Therapy in Acute Myocardial Infarction1979
  5. 5MORTALITY, MORBIDITY AND TREATMENT OF MYOCARDIAL INFARCTION: A REVIEW OF 455 CASES1953 · 11 citations