Higher estimated whole blood viscosity (third tertile) was associated with an increased occurrence of in-hospital and long-term major adverse cardiovascular events over a median 34.6 months in STEMI.
Cohort (n=1,835)
Does estimated whole blood viscosity predict in-hospital and long-term MACE in patients with STEMI?
Estimated whole blood viscosity using de Simone's formula may serve as a feasible prognostic indicator for short- and long-term MACE in patients with STEMI.
BACKGROUND: We assessed the predictive value of estimated whole blood viscosity (WBV) in-hospital and long-term cardiovascular outcomes in patients with ST-elevation myocardial infarction (STEMI). MATERIALS & METHODS: One thousand eight hundred and thirty-five STEMI patients were followed up for median 34.6 months. WBV was calculated consistent with the de Simone's formula. RESULTS: In-hospital and long-term major adverse cardiovascular events (MACE) demonstrated an incremental trend in ascending order of WBV tertiles at low and high shear rate. Kaplan-Meier analysis showed a higher occurrence of long-term MACE in third WBV tertiles compared with other tertiles. CONCLUSION: WBV seems to be a feasible prognostic indicator of short- and long-term cardiovascular adverse events in patients with STEMI. As an easily available parameter, WBV may be utilized in identifying high-risk patients for subsequent MACE.
Çetin et al. (Wed,) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=1,835). Whole blood viscosity (WBV) estimated by De Simone's formula vs. Lower WBV tertiles was evaluated on In-hospital and long-term major adverse cardiovascular events (MACE). Higher estimated whole blood viscosity (third tertile) was associated with an increased occurrence of in-hospital and long-term major adverse cardiovascular events over a median 34.6 months in STEMI.