In patients undergoing atrial fibrillation ablation, comorbid chronic obstructive pulmonary disease was associated with an increased risk of 180-day all-cause readmission (aHR 1.40) but not readmission due to recurrent AF.
Cohort (n=18,224)
Yes
Does a diagnosis of COPD increase the risk of readmission and complications in patients undergoing catheter ablation for atrial fibrillation?
In patients undergoing atrial fibrillation ablation, comorbid COPD is associated with higher all-cause readmission and periprocedural complications, but not with an increased risk of readmission for recurrent AF.
Effect estimate: aHR 1.40 (95% CI 1.26-1.56)
Absolute Event Rate: 44% vs 25%
p-value: p=<0.001
There is a paucity of contemporary data studying the association between COPD and outcomes of AF ablation. The objective of this study was to investigate the impact of COPD on AF ablation outcomes using a large nationwide database. This study was a retrospective analysis of the National Readmission Database for the years 2016-2018 and included patients admitted with a diagnosis of AF who underwent catheter ablation. Admissions were stratified according to COPD diagnosis using International Classification of Diseases, 10th Revision, Clinical Modification codes. Multivariate, linear, Cox, and logistic regressions were performed to study the impact of COPD on AF ablation. A total of 18,224 admissions (mean age, 68 years; standard deviation, 10 years) were included, of whom 3,494 (19%) had a diagnosis of COPD. The COPD group was older (72 8 vs. 67 11 years, P < .001) and more likely to have congestive heart failure (73% vs. 44%, P < .001) and renal failure (31% vs. 17%, P < .001).
Maraey et al. (2022) conducted a cohort in Atrial Fibrillation (n=18,224). Chronic Obstructive Pulmonary Disease (COPD) vs. No COPD was evaluated on 180-day all-cause readmission (aHR 1.40, 95% CI 1.26-1.56, p=<0.001). In patients undergoing atrial fibrillation ablation, comorbid chronic obstructive pulmonary disease was associated with an increased risk of 180-day all-cause readmission (aHR 1.40) but not readmission due to recurrent AF.