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February 1, 1999The Journal of Infectious Diseases165 citationsOpen Access

Ebola Hemorrhagic Fever and Pregnancy

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KMKibadi MupapaWMWoliere MukunduMBMpia Ado Bwaka

Key Points

  • This research investigates the effects of Ebola hemorrhagic fever on pregnancy outcomes.
  • Analyzed 105 women hospitalized for Ebola in Kikwit General Hospital.
  • Recorded pregnancy status and outcomes, including abortion and maternal mortality.
  • Examined treatment interventions such as curettage and blood transfusion.
  • 14% of women were pregnant, with 66% experiencing abortion.
  • Mortality rate among pregnant women was 95.5%, compared to 77% overall in the epidemic.
  • 4 pregnant women died during the third trimester.

Abstract

Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

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Cite This Study

Mupapa et al. (1999) studied this question.

synapsesocial.com/papers/6a1bc617666b677c61a8f197https://doi.org/10.1086/514289
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