Does intravenous procaine amide improve supraventricular arrhythmias in patients with supraventricular arrhythmias?
Intravenous procaine amide is effective for converting supraventricular arrhythmias like atrial fibrillation but is associated with significant electrocardiographic and hypotensive adverse effects.
The effect of the intravenous administration of procaine amide in 25 patients with supraventricular arrhythmias is reported. The data, including six conversions of auricular fibrillation, indicate a pronounced effect of this drug on the auricles as well as on the heart as a whole. Special attention is directed to the finding of frequent and undesirable electrocardiographic and hypotensive effects of this drug.
McCord et al. (Sat,) studied this question.
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