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The effect of the intravenous administration of procaine amide in 25 patients with supraventricular arrhythmias is reported. The data, including six conversions of auricular fibrillation, indicate a pronounced effect of this drug on the auricles as well as on the heart as a whole. Special attention is directed to the finding of frequent and undesirable electrocardiographic and hypotensive effects of this drug.
McCord et al. (Sat,) studied this question.