Why the study?
Does intermittent intravenous procainamide safely abolish ventricular arrhythmias and what is the effective plasma concentration range in patients with ventricular arrhythmias?
Population
20 patients with ventricular arrhythmias
Design
Case_series
Authors
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May inform procainamide dosing strategies; leaves open confirmation of safety and efficacy in randomized trials.
Does intermittent intravenous procainamide safely abolish ventricular arrhythmias and what is the effective plasma concentration range in patients with ventricular arrhythmias?
Intermittent intravenous procainamide rapidly and safely achieves antiarrhythmic plasma concentrations (4-10 µg/ml) to abolish ventricular arrhythmias.
Elsa‐Grace V. Giardina (1973) studied this question.
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