Why the study?
Does intravenous procaine amide abolish coupled ventricular premature depolarizations in affected patients?
Population
9 patients with coupled ventricular premature depolarizations (VPDs)
Design
Case_series
Authors
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May support procainamide for coupled VPDs in refractory cases; hypothesis-generating and requires randomized confirmation before practice change.
Does intravenous procaine amide abolish coupled ventricular premature depolarizations in affected patients?
Intravenous procaine amide abolishes coupled ventricular premature depolarizations by progressively increasing the coupling interval, suggesting it prolongs conduction in re-entrant pathways.
Giardina et al. (1973) studied this question.
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