Concomitant epicardial left atrial appendage ligation and left atrial ablation achieved stable sinus rhythm in 78% of patients at 12 months, demonstrating feasibility with an acceptable safety profile.
Observational (n=9)
No
Does concomitant epicardial LAA ligation and left atrial ablation improve rhythm outcomes and safety in patients with persistent AF?
Concomitant epicardial LAA ligation and left atrial ablation is feasible in selected patients with persistent AF, resulting in 78% sinus rhythm at 12 months, though safety requires further validation.
INTRODUCTION: We present initial results of patients undergoing a combined procedure of epicardial LAA ligation in addition to left atrial ablation for AF. METHODS: 9 patients were included for additional use of LARIAT as an individual treatment approach for AF. First an epicardial LAA ligation was performed, in the same procedure left atrial ablations consisting of PVI and additional substrate based modifying ablations were performed. Follow-up at 3 months and 12 months was performed. RESULTS: There was only 1 minor procedural complication (11%) involving epicardial bleeding and 2 late adverse events of pericardial tamponade and stroke. At the final follow-up (median 20 months) 7 patients were in stable sinus rhythm (78%) and 2 pts had reduced AF burden. CONCLUSION: Concomitant epicardial LAA ligation and ablation is feasible in selected patients with a reasonable risk profile. More prospective data are required to validate the safety and efficacy.
Nentwich et al. (Fri,) conducted a observational in Persistent atrial fibrillation (n=9). Concomitant epicardial LAA ligation and left atrial ablation was evaluated on Stable sinus rhythm at 12 months. Concomitant epicardial left atrial appendage ligation and left atrial ablation achieved stable sinus rhythm in 78% of patients at 12 months, demonstrating feasibility with an acceptable safety profile.
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