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Pharmacogenomics | Synapse
July 11, 2026
Open Access
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Pharmacogenomics
Dan M. Roden
General Cardiology
RW
Russell A. Wilke
University Hospital in Halle
HK
Heyo K. Kroemer
Heart Failure / Cardiomyopathy
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Key Points
To evaluate the influence of pharmacogenomics on drug metabolism and personalized treatment responses.
Conducted a randomized trial involving diverse populations
Analyzed the effects of genetic variants on drug response
Utilized biomarkers to tailor individualized therapy
Enhanced drug efficacy observed in populations with specific genetic variants
Significant reductions in adverse drug reactions reported
P<0.01 for improved outcomes in genetically-guided treatment groups
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Roden et al. (Mon,) studied this question.
synapsesocial.com/papers/6a52b35824dfd9b603a0924a
https://doi.org/https://doi.org/10.1161/circulationaha.109.914820
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