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December 16, 2010The Primary Care Companion to The Journal of Clinical Psychiatry119 citations

The P4 Screener

PDPriyanka DubeKKKurt KroenkeMBMatthew J. Bair

Key Result

The P4 screener triggered a suicide assessment in 17.6% of primary care and 16.5% of oncology patients, with the majority classified as minimal risk and only 0.4% to 1.6% as higher risk.

Study Design

Type

RCT (n=559)

Randomization

Randomized

Structured PICO

Does the P4 screener effectively assess potential suicide risk in primary care and oncology patients?

P
Population
559 primary care and oncology patients from two randomized trials, assessed for potential suicide ideation over 12 months.
I
Intervention
P4 screener (assessing past suicide attempts, suicide plan, probability of completing suicide, and preventive factors)
O
Outcome
Evaluation of preliminary evidence for the P4 screener as a brief measure to assess potential suicide riskpatient reported

The P4 screener may be a useful brief measure for assessing potential suicide risk in clinical care and research settings.

Abstract

BACKGROUND: Depression is the most common mental disorder, and suicide is its most serious consequence. The primary objective of this study was to evaluate preliminary evidence for the P4 screener as a brief measure to assess potential suicide risk. METHOD: The P4 screener was prospectively evaluated in 2 randomized effectiveness trials of primary care (January 2005-June 2008; N = 250) and oncology patients (March 2006-August 2009; N = 309). Potential suicide ideation was assessed at 5 time points in both trials: baseline and 1, 3, 6, and 12 months. The P4 screener asks about the "4 P's": past suicide attempts, suicide plan, probability of completing suicide, and preventive factors. Patients were classified as minimal, lower, and higher risk based upon responses to these 4 items. RESULTS: A suicide assessment was triggered 1 or more times by 17.6% (44 of 250) of Stepped Care for Affective Disorders and Musculoskeletal Pain (SCAMP) participants and 16.5% (51 of 309) of Indiana Cancer Pain and Depression (INCPAD) participants at some point in the trial. Of the patients who triggered a suicide assessment, the majority (29 of 44 in SCAMP and 27 of 51 in INCPAD) were classified as minimal risk by the algorithm. Only 1 (0.4%) of the SCAMP participants and 5 (1.6%) of the INCPAD participants were classified as higher risk. Among the latter, the most common factors preventing patients from attempting suicide were the "4 F's": faith, family, future hope, and fear of failing in their attempt. CONCLUSIONS: Preliminary findings suggest that the P4 screener may be useful in assessing potential suicide risk in the clinical care of depressed patients as well as in clinical research. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00118430 (SCAMP) and NCT00313573 (INCPAD).

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Cite This Study

Dube et al. (2010) conducted an RCT in Depression and potential suicide risk (n=559). P4 screener was evaluated on Suicide assessment triggered and risk classification. The P4 screener triggered a suicide assessment in 17.6% of primary care and 16.5% of oncology patients, with the majority classified as minimal risk and only 0.4% to 1.6% as higher risk.

synapsesocial.com/papers/6a63d1c92679aa42c5384e52https://doi.org/10.4088/pcc.10m00978blu
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Screening for Depression in Adults: A Summary of the Evidence for the U.S. Preventive Services Task Force2002 · 1,103 citations
  2. 2Outcomes of a Depression Screening and Postscreen Intervention Pilot Program in Specialty Clinics2024
  3. 3Feasibility and Acceptability of a Prevention-Focused Screener for Perinatal Depression Risk: Mixed Methods Cohort Study2026
  4. 4Suicidality Screening: Ensuring Providers Do Not Miss Adolescents at High Risk through Clinical Decision Support.2025
  5. 5Development and validation of the SuPr-10 questionnaire for suicidality assessment in primary care patients with depressive symptoms2026