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← Steven A. Rosenberg

Papers by Steven A. Rosenberg

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  1. T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapyProceedings of the National Academy of Sciences · 2013
  2. Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene TherapyJournal of Immunotherapy · 2013
  3. Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanomaBMC Genomics · 2012
  4. The Stoichiometric Production of IL-2 and IFN-γ mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in HumansScience Translational Medicine · 2012
  5. IRF5 gene polymorphisms in melanomaJournal of Translational Medicine · 2012
  6. Myeloid Cells Obtained from the Blood but Not from the Tumor Can Suppress T-cell Proliferation in Patients with MelanomaClinical Cancer Research · 2012
  7. Recognition of Glioma Stem Cells by Genetically Modified T Cells Targeting EGFRvIII and Development of Adoptive Cell Therapy for GliomaHuman Gene Therapy · 2012
  8. TIL therapy broadens the tumor-reactive CD8⁺T cell compartment in melanoma patientsOncoImmunology · 2012
  9. Minimally invasive liver resection to obtain tumor-infiltrating lymphocytes for adoptive cell therapy in patients with metastatic melanomaWorld Journal of Surgical Oncology · 2012
  10. Two Hundred Years of Cancer ResearchNew England Journal of Medicine · 2012
  11. Audiovestibular Dysfunction Associated with Adoptive Cell Immunotherapy for MelanomaOtolaryngology · 2012
  12. Tumor-specific CD4+ Melanoma Tumor-infiltrating LymphocytesJournal of Immunotherapy · 2012
  13. Evaluation of γ-Retroviral Vectors That Mediate the Inducible Expression of IL-12 for Clinical ApplicationJournal of Immunotherapy · 2012
  14. Levels of peripheral CD4+FoxP3+ regulatory T cells are negatively associated with clinical response to adoptive immunotherapy of human cancerBlood · 2012
  15. Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serumBlood · 2012
  16. Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE® bioreactorJournal of Translational Medicine · 2012
  17. A Simple and Effective Method to Generate Lentiviral Vectors for Ex Vivo Gene Delivery to Mature Human Peripheral Blood LymphocytesHuman Gene Therapy Methods · 2012
  18. Raising the Bar: The Curative Potential of Human Cancer ImmunotherapyScience Translational Medicine · 2012
  19. New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancerJournal of Translational Medicine · 2012
  20. Simplified Method of the Growth of Human Tumor Infiltrating Lymphocytes in Gas-permeable Flasks to Numbers Needed for Patient TreatmentJournal of Immunotherapy · 2012
  21. Replication-Competent Retroviruses in Gene-Modified T Cells Used in Clinical Trials: Is It Time to Revise the Testing Requirements?Molecular Therapy · 2012
  22. Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in MiceClinical Cancer Research · 2012
  23. CTLA-4 Blockade with Ipilimumab: Long-term Follow-up of 177 Patients with Metastatic MelanomaClinical Cancer Research · 2012
  24. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cellsBlood · 2011
  25. IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumorsJournal of Clinical Investigation · 2011
  26. Personalized Cell Transfer Immunotherapy for B-Cell Malignancies and Solid CancersMolecular Therapy · 2011
  27. Augmented Lymphocyte Expansion from Solid Tumors With Engineered Cells for Costimulatory EnhancementJournal of Immunotherapy · 2011
  28. Mutational Inactivation of STAG2 Causes Aneuploidy in Human CancerScience · 2011
  29. Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor RegressionClinical Cancer Research · 2011
  30. The Shedding of CD62L (L-Selectin) Regulates the Acquisition of Lytic Activity in Human Tumor Reactive T LymphocytesPLoS ONE · 2011
  31. Determinants of Successful CD8+ T-Cell Adoptive Immunotherapy for Large Established Tumors in MiceClinical Cancer Research · 2011
  32. An antigenic peptide produced by reverse splicing and double asparagine deamidationProceedings of the National Academy of Sciences · 2011
  33. gp100 Peptide Vaccine and Interleukin-2 in Patients with Advanced MelanomaNew England Journal of Medicine · 2011
  34. Considerations for the Clinical Application of Chimeric Antigen Receptor T Cells: Observations from a Recombinant DNA Advisory Committee Symposium Held June 15, 2010Cancer Research · 2011
  35. Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer ImmunotherapyClinical Cancer Research · 2011
  36. Irradiation Enhances Human T-cell Function by Upregulating CD70 Expression on Antigen-presenting Cells In VitroJournal of Immunotherapy · 2011
  37. Genetic Engineering of Murine CD8+ and CD4+ T Cells for Preclinical Adoptive Immunotherapy StudiesJournal of Immunotherapy · 2011
  38. Assessment of Ovarian Function After Preparative Chemotherapy and Total Body Radiation for Adoptive Cell TherapyJournal of Immunotherapy · 2011
  39. Surgical management of melanoma brain metastases in patients treated with immunotherapyJournal of neurosurgery · 2011
  40. CARs on Track in the ClinicMolecular Therapy · 2011
  41. Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanomaHuman Mutation · 2011
  42. Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1Journal of Clinical Oncology · 2011
  43. Improving Adoptive T Cell Therapy by Targeting and Controlling IL-12 Expression to the Tumor EnvironmentMolecular Therapy · 2011
  44. T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient ColitisMolecular Therapy · 2010
  45. A TCR Targeting the HLA-A*0201–Restricted Epitope of MAGE-A3 Recognizes Multiple Epitopes of the MAGE-A Antigen Superfamily in Several Types of CancerThe Journal of Immunology · 2010
  46. Development of Human Anti-Murine T-Cell Receptor Antibodies in Both Responding and Nonresponding Patients Enrolled in TCR Gene Therapy TrialsClinical Cancer Research · 2010
  47. Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in miceJournal of Clinical Investigation · 2010
  48. Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapyBlood · 2010
  49. Mutational and Functional Analysis Reveals ADAMTS18 Metalloproteinase as a Novel Driver in MelanomaMolecular Cancer Research · 2010
  50. Selection of CD8+PD-1+ Lymphocytes in Fresh Human Melanomas Enriches for Tumor-reactive T CellsJournal of Immunotherapy · 2010