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← David Baltimore

Papers by David Baltimore

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  1. Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-ToleranceThe Journal of Immunology · 2003
  2. Enhanced: The Need for a Global HIV Vaccine EnterpriseScience · 2003
  3. Chimeric Nucleases Stimulate Gene Targeting in Human CellsScience · 2003
  4. Efficient Gene Targeting Mediated by Adeno-Associated Virus and DNA Double-Strand BreaksMolecular and Cellular Biology · 2003
  5. Essential and dispensable roles of ATR in cell cycle arrest and genome maintenanceGenes & Development · 2003
  6. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5Proceedings of the National Academy of Sciences · 2002
  7. The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene ActivationScience · 2002
  8. Generation of functional antigen-specific T cells in defined genetic backgrounds by retrovirus-mediated expression of TCR cDNAs in hematopoietic precursor cellsProceedings of the National Academy of Sciences · 2002
  9. The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cellsProceedings of the National Academy of Sciences · 2002
  10. Cooperation of multiple signaling pathways in CD40-regulated gene expression in B lymphocytesProceedings of the National Academy of Sciences · 2002
  11. Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral VectorsScience · 2002
  12. Requirement for the NF-κB Family Member RelA in the Development of Secondary Lymphoid OrgansThe Journal of Experimental Medicine · 2002
  13. Targeted Mutation of TNF Receptor I Rescues the RelA-Deficient Mouse and Reveals a Critical Role for NF-κB in Leukocyte RecruitmentThe Journal of Immunology · 2001
  14. Domain-dependent Function of the rasGAP-binding Protein p62Dok in Cell SignalingJournal of Biological Chemistry · 2001
  15. Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and BtkThe Journal of Experimental Medicine · 2000
  16. Selective requirement for c-Rel during IL-12 P40 gene induction in macrophagesProceedings of the National Academy of Sciences · 2000
  17. Retroviral Expression in Embryonic Stem Cells and Hematopoietic Stem CellsMolecular and Cellular Biology · 2000
  18. V(D)J recombination is not activated by demethylation of the kappa locusProceedings of the National Academy of Sciences · 2000
  19. The Human Thioesterase II Protein Binds to a Site on HIV-1 Nef Critical for CD4 Down-regulationJournal of Biological Chemistry · 2000
  20. ATR disruption leads to chromosomal fragmentation and early embryonic lethalityGenes & Development · 2000
  21. Role of the rasGAP-associated docking protein p62dokin negative regulation of B cell receptor-mediated signalingGenes & Development · 2000
  22. The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defectsProceedings of the National Academy of Sciences · 1999
  23. Chromatin remodeling directly activates V(D)J recombinationProceedings of the National Academy of Sciences · 1999
  24. HIV's evasion of the cellular immune responseImmunological Reviews · 1999
  25. Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-AblJournal of Biological Chemistry · 1999
  26. Specificities of CD40 signaling: Involvement of TRAF2 in CD40-induced NF-κB activation and intercellular adhesion molecule-1 up-regulationProceedings of the National Academy of Sciences · 1999
  27. Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activationProceedings of the National Academy of Sciences · 1999
  28. The p65 Subunit of NF-κB Is Redundant with p50 During B Cell Proliferative Responses, and Is Required for Germline CH Transcription and Class Switching to IgG3The Journal of Immunology · 1999
  29. Essential Roles for the Abl and Arg Tyrosine Kinases in NeurulationNeuron · 1998
  30. Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone MarrowBlood · 1998
  31. Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone MarrowBlood · 1998
  32. Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by the Adapter Protein DaxxScience · 1998
  33. Essential Role of CED-4 Oligomerization in CED-3 Activation and ApoptosisScience · 1998
  34. Involvement of p53 and p21 in Cellular Defects and Tumorigenesis in Atm−/− MiceMolecular and Cellular Biology · 1998
  35. HIV-1 Directly Kills CD4+ T Cells by a Fas-independent MechanismThe Journal of Experimental Medicine · 1998
  36. Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia–telangiectasiaProceedings of the National Academy of Sciences · 1997
  37. Interleukin 3-dependent survival by the Akt protein kinaseProceedings of the National Academy of Sciences · 1997
  38. Localization of the Major NF-κB-activating Site and the Sole TRAF3 Binding Site of LMP-1 Defines Two Distinct Signaling MotifsJournal of Biological Chemistry · 1997
  39. The kappaB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growthJournal of Virology · 1997
  40. p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50−/−relB−/−Double-knockout MiceThe Journal of Experimental Medicine · 1997
  41. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell DeathScience · 1996
  42. Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependentThe Journal of Immunology · 1996
  43. Dual roles of ATM in the cellular response to radiation and in cell growth control.Genes & Development · 1996
  44. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma.Genes & Development · 1996
  45. CD4 down-modulation during infection of human T cells with human immunodeficiency virus type 1 involves independent activities of vpu, env, and nefJournal of Virology · 1996
  46. Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.Genes & Development · 1996
  47. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.The Journal of Experimental Medicine · 1996
  48. TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.Genes & Development · 1996
  49. Regulation of 3’ IgH enhancers by a common set of factors, including kappa B-binding proteinsThe Journal of Immunology · 1996
  50. Genetic evidence that the RAG1 protein directly participates in V(D)J recombination through substrate recognition.Proceedings of the National Academy of Sciences · 1996