James H. Doroshow

Cardio-Oncology

National Institutes of Health

About

James H. Doroshow works in Cardio-Oncology affiliated with National Institutes of Health.

James H. Doroshow serves as the Director of the Division of Cancer Treatment and Diagnosis at the National Cancer Institute, National Institutes of Health. He previously held the position of Chairman of the Department of Medical Oncology and Therapeutics Research at City of Hope Comprehensive Cancer Center from 1983 to 2004. His research includes investigations into the cardiac toxicity of cancer therapeutics, focusing on oxidative stress and reactive oxygen metabolism in heart cells.

Research focus

Anthracycline-induced cardiotoxicityReactive oxygen species in cardiac myocytesOxidative stress mechanisms in heart tissueCardiac effects of anticancer quinonesEnzymatic defenses against drug-induced cardiac damage

Impact

1,410 pubs · 37,273 cites · h-index 96

Training

Bachelor's
Harvard College
1969
MD
Harvard Medical School
1973

Affiliations

Work Experience

Director, Division of Cancer Treatment and Diagnosis

National Cancer Institute · 2004 - Present

Deputy Director for Clinical and Translational Research

National Cancer Institute · 2011 - 2024

Chairman, Department of Medical Oncology and Therapeutics Research

City of Hope Comprehensive Cancer Center · 1983 - 2004

Assistant Professor of Medicine, Division of Medical Oncology

University of Southern California School of Medicine