| 1 | 2022 AHA/ACC Key Data Elements and Definitions for Cardiovascular and Noncardiovascular Complications of COVID-19 Journal of the American College of Cardiology · Bozkurt B et al. | Jun 23 | | Yes (ACC Journal Scan (X)) | — | — | — | — |
| 2 | Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention New England Journal of Medicine · Perera D et al. | Mar 29 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 3 | High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial European Heart Journal · Peña J et al. | Dec 20 | | Yes (European Heart Journal) | — | — | — | — |
| 4 | Conservative Oxygen for Unresponsive Patients after Cardiac Arrest New England Journal of Medicine · Group T et al. | Jun 10 | | Yes (NEJM) | — | — | — | — |
| 5 | Artificial intelligence in the diagnosis and management of arrhythmias European Heart Journal · Nagarajan V et al. | Jul 26 | | Yes (European Heart Journal) | — | — | — | — |
| 6 | Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation New England Journal of Medicine · Doshi S et al. | Mar 28 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 7 | Case 16-2026: A 14-Year-Old Girl with Hypertension New England Journal of Medicine · Osborn R et al. | Jun 10 | | Yes (NEJM) | — | — | — | — |
| 8 | Heart Failure With Preserved Ejection Fraction and Diabetes Journal of the American College of Cardiology · McHugh K et al. | Feb 1 | | Yes (JACC) | — | — | — | — |
| 9 | Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T) Journal of the American College of Cardiology · Alvi R et al. | Dec 1 | | Yes (JACC) | — | — | — | — |
| 10 | Amara Yad Image: Sectional View of the Left Ventricular Outflow Tract Viewed From the Inferior Direction Journal of the American College of Cardiology · Goel N et al. | Apr 1 | | Yes (JACC) | — | — | — | — |
| 11 | Sirolimus-Coated Balloon Angioplasty for Infrainguinal Artery Disease New England Journal of Medicine · Barco S et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 12 | RND3 Enhances Cardiac Glucose Metabolism Through Inhibiting ACAT1-Dependent PDHA1 Acetylation and Protects Against Ischemia-Reperfusion Injury Circulation · Xiong Z et al. | Jun 11 | | Yes (Circulation) | — | — | — | — |
| 13 | Effect of APOC3 Inhibition with Olezarsen on Coronary Atherosclerosis: Essence–TIMI 73b Imaging Study Circulation · Marston N et al. | Mar 30 | — | Yes (Circulation) | — | Yes (TWiC) | — | — |
| 14 | Discontinuation of Beta-Blocker Therapy after Myocardial Infarction New England Journal of Medicine · Choi K et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 15 | Angiotensin-Converting Enzyme Inhibitors in Hypertension Journal of the American College of Cardiology · Messerli F et al. | Apr 1 | | Yes (JACC) | — | — | — | — |
| 16 | Mavacamten in Adolescents with Obstructive Hypertrophic Cardiomyopathy New England Journal of Medicine · Rossano J et al. | Mar 29 | | Yes (NEJM) | — | — | — | — |
| 17 | Consideration of a New Definition of Clinically Relevant Myocardial Infarction After Coronary Revascularization Journal of the American College of Cardiology · Moussa I et al. | Oct 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 18 | Familial Hypercholesterolemia Journal of the American College of Cardiology · Brandts J et al. | Oct 25 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 19 | Management of Mechanical Prosthetic Heart Valve Thrombosis Journal of the American College of Cardiology · Jiménez C et al. | May 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 20 | Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism New England Journal of Medicine · Rosenfield K et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 21 | Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease New England Journal of Medicine · Lee Y et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 22 | IVUS-Guided versus Angiography-Guided PCI in Unprotected Left Main Coronary Disease New England Journal of Medicine · Testa L et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 23 | Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI New England Journal of Medicine · Diletti R et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 24 | Multicenter Randomized Trial Evaluating the Efficacy of Cilostazol on Ischemic Vascular Complications After Drug-Eluting Stent Implantation for Coronary Heart Disease Journal of the American College of Cardiology · Suh J et al. | Jan 1 | | Yes (JACC) | — | — | — | — |
| 25 | Association between Triglyceride-glucose (TyG) Index and Risk of Stroke Recurrence and Mortality: A Systematic Review and Meta-analysis (P4-5.001) Neurology · Malik D et al. | Jun 9 | | — | — | — | — | — |
| 26 | Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients European Heart Journal · Desai A et al. | May 28 | | Yes (European Heart Journal) | — | — | — | — |
| 27 | All-Cause Mortality and Cardiovascular Outcomes With Prophylactic Steroid Therapy in Duchenne Muscular Dystrophy Journal of the American College of Cardiology · Schram G et al. | Jan 23 | | Yes (JACC) | — | — | — | — |
| 28 | Analysis of Worsening Heart Failure Events in an Integrated Health Care System Journal of the American College of Cardiology · Ambrosy A et al. | Jul 1 | | Yes (JACC) | — | — | — | — |
| 29 | Early Surgery for Asymptomatic Aortic Stenosis at 10 Years New England Journal of Medicine | Jun 10 | — | Yes (NEJM) | — | — | — | — |
| 30 | Mortality Benefit of Rivaroxaban Plus Aspirin in Patients With Chronic Coronary or Peripheral Artery Disease Journal of the American College of Cardiology · Eikelboom J et al. | Jun 28 | | Yes (JACC) | — | — | — | — |
| 31 | Polypharmacy in Older Adults Hospitalized for Heart Failure Circulation Heart Failure · Ünlü O et al. | Oct 13 | — | Yes (ACC Journal Scan) | 4 | — | — | — |
| 32 | Chronic Thromboembolic Pulmonary Hypertension Journal of the American College of Cardiology · Papamatheakis D et al. | Oct 26 | | Yes (JACC) | — | — | — | — |
| 33 | Challenges in assessing statin-associated adverse events The Lancet · Rovetta A et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 34 | Challenges in assessing statin-associated adverse events The Lancet · Bijl M et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 35 | Challenges in assessing statin-associated adverse events – Authors’ reply The Lancet · Reith C et al. | Jun 1 | — | Yes (The Lancet) | — | — | — | — |
| 36 | Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction Journal of the American College of Cardiology · Tromp J et al. | Aug 27 | | Yes (JACC) | — | — | — | — |
| 37 | Cardiac rehabilitation patient perspectives during COVID-19 pandemic Jug B et al. | Jun 8 | | — | — | — | — | — |
| 38 | PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction European Heart Journal · Dalt L et al. | Jun 24 | — | Yes (European Heart Journal) | — | — | — | — |
| 39 | Relationship of PCSK9 and Urinary Thromboxane Excretion to Cardiovascular Events in Patients With Atrial Fibrillation Journal of the American College of Cardiology · Pastori D et al. | Sep 1 | — | Yes (JACC) | — | — | — | — |
| 40 | The PCSK9-LDL Receptor Axis and Outcomes in Heart Failure Journal of the American College of Cardiology · Bayés‐Genís A et al. | Oct 1 | — | Yes (JACC) | — | — | — | — |
| 41 | Quantifying Triglyceride-Rich Lipoprotein Atherogenicity, Associations With Inflammation, and Implications for Risk Assessment Using Non-HDL Cholesterol Journal of the American College of Cardiology · Björnson E et al. | Sep 23 | — | Yes (JACC) | — | — | — | — |
| 42 | A Comprehensive Review of Cardiovascular Disease Prediction Using ECG Image Processing and Ensemble Machine Learning Techniques M P et al. | Jun 11 | | — | — | — | — | — |
| 43 | Machine Learning-Based Prediction of Death and Hospitalization in Patients With Implantable Cardioverter Defibrillators Journal of the American College of Cardiology · Rosman L et al. | Nov 20 | — | Yes (JACC) | — | — | — | — |
| 44 | Left Ventricular Unloading in Anterior STEMI without Shock: The STEMI Door to Unload (DTU) Randomized Controlled Trial Journal of the American College of Cardiology · Kapur N et al. | Mar 1 | — | Yes (JACC) | — | — | — | — |
| 45 | Sotatercept for Combined Post- and Pre-capillary Pulmonary Hypertension Associated With Heart Failure: Results from the Phase 2, Randomized, Placebo-Controlled CADENCE Study Circulation · Gomberg-Maitland M et al. | Mar 29 | — | Yes (Circulation) | — | — | — | — |
| 46 | Reduced risk of gastrointestinal bleeding associated with proton pump inhibitor therapy in patients treated with dual antiplatelet therapy after myocardial infarction European Heart Journal · Sehested T et al. | Feb 18 | — | Yes (European Heart Journal) | — | — | — | — |
| 47 | Association between self-care behaviour and multiple frailty domains in older patients with heart failure European Heart Journal · Matsui A et al. | Oct 1 | — | Yes (European Heart Journal) | — | — | — | — |
| 48 | Unusual rapid progression of non-bacterial thrombotic endocarditis in a patient with bladder cancer despite undergoing intensification treatment with rivaroxaban for acute venous thromboembolism European Heart Journal · Fujimoto D et al. | Aug 23 | — | Yes (European Heart Journal) | — | — | — | — |
| 49 | Arrhythmic risk stratification in post-myocardial infarction patients with preserved ejection fraction: the PRESERVE EF study European Heart Journal · Gatzoulis K et al. | Apr 11 | — | Yes (European Heart Journal) | — | — | — | — |
| 50 | Prognosis of “Masked” Hypertension and “White-Coat” Hypertension Detected by 24-h Ambulatory Blood Pressure Monitoring Journal of the American College of Cardiology · Ohkubo T et al. | Jul 13 | — | Yes (JACC) | — | — | — | — |