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April 21, 20260 citations

Metabolic syndrome in chronic schizophrenia: Cross-sectional hospital assessment of prolonged risperidone exposure.

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YWYimin WuGanzhou People's HospitalJWJie WuGanzhou People's HospitalDZDeng ZuobinGanzhou People's Hospital

Key Points

  • This study aims to compare the risk of metabolic syndrome associated with long-term risperidone therapy versus olanzapine in patients with chronic schizophrenia.
  • Conducted a cross-sectional assessment of patients exposed to risperidone for an extended period.
  • Evaluated metabolic syndrome risk in comparison to olanzapine-treated patients.
  • Recommended regular metabolic monitoring and interventions for high-risk individuals.
  • Long-term risperidone therapy is linked to a lower risk of metabolic syndrome compared to olanzapine.
  • Regular metabolic monitoring is advised for patients on risperidone, especially those at high risk.

Abstract

Long-term risperidone therapy is associated with a lower MetS risk than olanzapine. Regular metabolic monitoring and adjunctive interventions are recommended for high-risk patients.

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Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69e713decb99343efc98d4aahttps://doi.org/10.36721/pjps.2026.39.6.180.1
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