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May 9, 1998BMJ173 citationsOpen Access

Secondary prevention clinics for coronary heart disease: randomised trial of effect on health

NCNeil CampbellJTJ. ThainHDH G. Deans

Key Result

Nurse-led secondary prevention clinics reduced worsening chest pain (OR 0.59; 95% CI 0.37-0.94) and hospital admissions (OR 0.64; 95% CI 0.48-0.86) in patients with coronary heart disease.

Study Design

Type

RCT (n=1,173)

Multicenter

Yes

Structured PICO

Do nurse-led secondary prevention clinics improve health status and reduce hospital admissions in patients with coronary heart disease?

P
Population
1173 patients (685 men and 488 women) under 80 years with working diagnoses of coronary heart disease who did not have terminal illness or dementia and were not housebound, from 19 general practices in northeast Scotland.
I
Intervention
Secondary prevention clinics run by nurses in general practice promoting medical and lifestyle aspects of secondary prevention and offering regular follow up over one year.
O
Outcome
Health status measured by the SF-36 questionnaire, chest pain by the angina type specification, anxiety and depression by the hospital anxiety and depression scale, and use of health services before and during the study.patient reported

Nurse-led secondary prevention clinics in general practice significantly improve patient-reported health status and reduce hospital admissions in patients with coronary heart disease.

Main Result

Effect estimate: Adjusted difference 8.52 (95% CI 4.16-12.9)

Abstract

OBJECTIVE: To evaluate the effects of secondary prevention clinics run by nurses in general practice on the health of patients with coronary heart disease. DESIGN: Randomised controlled trial of clinics over one year with assessment by self completed postal questionnaires and audit of medical records at the start and end of the trial. SETTING: Random sample of 19 general practices in northeast Scotland. SUBJECTS: 1173 patients (685 men and 488 women) under 80 years with working diagnoses of coronary heart disease who did not have terminal illness or dementia and were not housebound. INTERVENTION: Clinic staff promoted medical and lifestyle aspects of secondary prevention and offered regular follow up. MAIN OUTCOME MEASURES: Health status measured by the SF-36 questionnaire, chest pain by the angina type specification, and anxiety and depression by the hospital anxiety and depression scale. Use of health services before and during the study. RESULTS: There were significant improvements in six of eight health status domains (all functioning scales, pain, and general health) among patients attending the clinic. Role limitations attributed to physical problems improved most (adjusted difference 8.52, 95% confidence interval 4.16 to 12. 9). Fewer patients reported worsening chest pain (odds ratio 0.59, 95% confidence interval 0.37 to 0.94). There were no significant effects on anxiety or depression. Fewer intervention group patients required hospital admissions (0.64, 0.48 to 0.86), but general practitioner consultation rates did not alter. CONCLUSIONS: Within their first year secondary prevention clinics improved patients' health and reduced hospital admissions.

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Cite This Study

Campbell et al. (1998) conducted an RCT in Coronary heart disease (n=1,173). Secondary prevention clinics run by nurses was evaluated on Health status (role limitations attributed to physical problems) (Adjusted difference 8.52, 95% CI 4.16-12.9). Nurse-led secondary prevention clinics reduced worsening chest pain (OR 0.59; 95% CI 0.37-0.94) and hospital admissions (OR 0.64; 95% CI 0.48-0.86) in patients with coronary heart disease.

synapsesocial.com/papers/6a073b3055897739608443f3https://doi.org/10.1136/bmj.316.7142.1434
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Secondary prevention in coronary heart disease: a randomised trial of nurse led clinics in primary care1998 · 260 citations
  2. 2Secondary prevention clinics for coronary heart disease: four year follow up of a randomised controlled trial in primary care2003 · 281 citations
  3. 3Secondary prevention clinics: improving quality of life and outcome2004 · 22 citations
  4. 4Secondary prevention for coronary artery disease2004 · 8 citations
  5. 5Cluster randomised controlled trial to compare three methods of promoting secondary prevention of coronary heart disease in primary care2001 · 184 citations