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April 6, 1999Circulation155 citations

Right Atrial Flutter Due to Lower Loop Reentry

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JCJie ChengWCW R CabeenMSMelvin M. Scheinman

Key Result

Lower-loop reentry is a subtype of right atrial flutter dependent on the TA-ER isthmus, characterized by a shorter cycle length than typical atrial flutter (217 vs 272 ms, P<0.01).

Key Points

  • This research aims to explore the mechanisms of a rapid subtype of atrial flutter known as lower-loop reentry.
  • Twenty-nine patients with atrial flutter were studied.
  • Atrial electrograms were recorded using a 20-pole catheter against the tricuspid annulus.
  • Linear ablation was performed to achieve bidirectional conduction block in the TA-ER isthmus.
  • Lower-loop reentry was induced in 3 patients and occurred spontaneously in 3 others.
  • The cycle length of lower-loop reentry was significantly shorter at 217±32 ms compared to typical atrial flutter at 272±40 ms (P<0.01).
  • Linear ablation successfully terminated spontaneous lower-loop reentry in 3 patients.

Study Design

Type

Observational (n=29)

Structured PICO

P
Population
29 patients with atrial flutter
I
Intervention
Electrophysiological mapping and linear ablation in the tricuspid annulus-eustachian ridge (TA-ER) isthmus
C
Comparator
Typical atrial flutter (within-patient comparison)
O
Outcome
Electrophysiological characteristics (cycle length) and response to ablation of lower-loop reentry (LLR) atrial fluttersurrogate

Lower-loop reentry is a distinct subtype of right atrial flutter dependent on the TA-ER isthmus, which can be effectively targeted by linear ablation.

Main Result

Absolute Event Rate: 217% vs 272%

p-value: p=<0.01

Abstract

BACKGROUND: The mechanisms of an atrial flutter (AFL) that is more rapid and at times more irregular than typical AFL are unknown. METHODS AND RESULTS: Twenty-nine patients with AFL were studied. Atrial electrograms were recorded from a 20-pole catheter placed against the tricuspid annulus (TA), with its distal electrodes lateral to the isthmus between the TA and the eustachian ridge (ER), and from the His bundle and coronary sinus catheters. Atrial extrastimuli were delivered in the TA-ER isthmus during typical AFL. Episodes of a right atrial flutter rhythm that was different from typical AFL were induced in 3 patients and occurred spontaneously in 3 patients. This sustained AFL, designated as lower-loop reentry (LLR), involved the lower right atrium (RA), as manifested by early breakthrough in the lower RA, wave-front collision in the high lateral RA or septum, and conduction through the TA-ER isthmus. Linear ablation resulting in bidirectional conduction block in the TA-ER isthmus terminated spontaneous LLR in 3 patients and rendered LLR noninducible in all patients. The cycle length of LLR was shorter than that of typical AFL (217+/-32 versus 272+/-40 ms, P<0. 01). Alternating LLR and typical AFL in 1 patient resulted in cycle length oscillation. CONCLUSIONS: LLR is a subtype of right atrial flutter and depends on conduction through the TA-ER isthmus.

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Cite This Study

Cheng et al. (1999) conducted an observational in Atrial flutter (n=29). Electrophysiological mapping and linear ablation vs. Typical atrial flutter was evaluated on Cycle length (p=<0.01). Lower-loop reentry is a subtype of right atrial flutter dependent on the TA-ER isthmus, characterized by a shorter cycle length than typical atrial flutter (217 vs 272 ms, P<0.01).

synapsesocial.com/papers/6a0f24ac14089a5783bdc13bhttps://doi.org/10.1161/01.cir.99.13.1700
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